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Transcriptional Regulator TetR21 Controls the Expression of the Staphylococcus aureus LmrS Efflux Pump

TetR21 controls the expression of Tet38 and LmrS efflux pumps. A tetR21 mutant, QT21, exhibited a 4-fold increase in the transcription level of lmrS. Staphylococcus aureus lmrS overexpressor showed increases of 4-fold and 2-fold, respectively, in the MICs of chloramphenicol and erythromycin, while t...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Truong-Bolduc, Q. C., Wang, Y., Chen, C., Hooper, D. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527640/
https://ncbi.nlm.nih.gov/pubmed/28584148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00649-17
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