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Staphylococcus aureus Tet38 Efflux Pump Structural Modeling and Roles of Essential Residues in Drug Efflux and Host Cell Internalization

The Staphylococcus aureus Tet38 membrane protein has distinct functions, including drug efflux and host cell attachment and internalization mediated by interaction with host cell CD36. Using structural modeling and site-directed mutagenesis, we identified key amino acids involved in different functi...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Truong-Bolduc, Q. C., Wang, Y., Hooper, D. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091097/
https://ncbi.nlm.nih.gov/pubmed/33619028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00811-20
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