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APOL1 risk variants affect podocyte lipid homeostasis and energy production in focal segmental glomerulosclerosis
Lipotoxicity was recently reported in several forms of kidney disease, including focal segmental glomerulosclerosis (FSGS). Susceptibility to FSGS in African Americans is associated with the presence of genetic variants of the Apolipoprotein L1 gene (APOL1) named G1 and G2. If and how endogenous APO...
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| Publicado en: | Hum Mol Genet |
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| Autores principales: | , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Oxford University Press
2021
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8091039/ https://ncbi.nlm.nih.gov/pubmed/33517446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddab022 |
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