APOL1 risk variants affect podocyte lipid homeostasis and energy production in focal segmental glomerulosclerosis

Lipotoxicity was recently reported in several forms of kidney disease, including focal segmental glomerulosclerosis (FSGS). Susceptibility to FSGS in African Americans is associated with the presence of genetic variants of the Apolipoprotein L1 gene (APOL1) named G1 and G2. If and how endogenous APO...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Hum Mol Genet
Autores principales: Ge, Mengyuan, Molina, Judith, Ducasa, G Michelle, Mallela, Shamroop K, Varona Santos, Javier, Mitrofanova, Alla, Kim, Jin-Ju, Liu, Xiaochen, Sloan, Alexis, Mendez, Armando J, Banerjee, Santanu, Liu, Shaoyi, Szeto, Hazel H, Shin, Myung K, Hoek, Maarten, Kopp, Jeffrey B, Fontanesi, Flavia, Merscher, Sandra, Fornoni, Alessia
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
Materias:
General Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8091039/
https://ncbi.nlm.nih.gov/pubmed/33517446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddab022
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares