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APOL1 risk variants affect podocyte lipid homeostasis and energy production in focal segmental glomerulosclerosis
Lipotoxicity was recently reported in several forms of kidney disease, including focal segmental glomerulosclerosis (FSGS). Susceptibility to FSGS in African Americans is associated with the presence of genetic variants of the Apolipoprotein L1 gene (APOL1) named G1 and G2. If and how endogenous APO...
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| Publicat a: | Hum Mol Genet |
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| Autors principals: | , , , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8091039/ https://ncbi.nlm.nih.gov/pubmed/33517446 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddab022 |
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