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Discoidin domain receptor 1 activation links extracellular matrix to podocyte lipotoxicity in Alport syndrome
BACKGROUND: Discoidin domain receptor 1 (DDR1) is a receptor tyrosine kinase that is activated by collagens that is involved in the pathogenesis of fibrotic disorders. Interestingly, de novo production of the collagen type I (Col I) has been observed in Col4a3 knockout mice, a mouse model of Alport...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | EBioMedicine |
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| Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Elsevier
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7750578/ https://ncbi.nlm.nih.gov/pubmed/33340991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2020.103162 |
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