A necessary role of DNMT3A in endurance exercise by suppressing ALDH1L1‐mediated oxidative stress

Exercise can alter the skeletal muscle DNA methylome, yet little is known about the role of the DNA methylation machinery in exercise capacity. Here, we show that DNMT3A expression in oxidative red muscle increases greatly following a bout of endurance exercise. Muscle‐specific Dnmt3a knockout mice...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:EMBO J
Egile Nagusiak: Damal Villivalam, Sneha, Ebert, Scott M, Lim, Hee Woong, Kim, Jinse, You, Dongjoo, Jung, Byung Chul, Palacios, Hector H, Tcheau, Tabitha, Adams, Christopher M, Kang, Sona
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2021
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090849/
https://ncbi.nlm.nih.gov/pubmed/33847380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106491
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