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A necessary role of DNMT3A in endurance exercise by suppressing ALDH1L1‐mediated oxidative stress
Exercise can alter the skeletal muscle DNA methylome, yet little is known about the role of the DNA methylation machinery in exercise capacity. Here, we show that DNMT3A expression in oxidative red muscle increases greatly following a bout of endurance exercise. Muscle‐specific Dnmt3a knockout mice...
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| Опубликовано в: : | EMBO J |
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| Главные авторы: | , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
John Wiley and Sons Inc.
2021
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8090849/ https://ncbi.nlm.nih.gov/pubmed/33847380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.2020106491 |
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