Sox2 Is Required Independently in Both Stem and Differentiated Cells for Pituitary Tumour Genesis in P27 Null Mice

Tumour development can depend on cell intrinsic dysfunction, but, in some cases, extrinsic factors are important drivers. Here, we have established a genetically tractable model demonstrating that the same gene is relevant both cell-autonomously and non-cell-autonomously for tumorigenesis. P27, a ce...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Endocr Soc
Autores principales: Moncho-Amor, Veronica, Chakravarty, Probir, Galichet, Christophe, Lovell-Badge, Robin, Rizzoti, Karine
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2021
Materias:
Genetics and Development (including Gene Regulation)
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090700/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1043
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares