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Nestin-Cre Mice Are Affected by Hypopituitarism, Which Is Not Due to Significant Activity of the Transgene in the Pituitary Gland

Nestin-Cre mice express Cre recombinase under control of the rat nestin promoter and central nervous system (CNS) enhancer. While endogenous Nestin is expressed in some other tissues including the pituitary gland, Nestin-Cre mice induce recombination predominantly in the CNS. For this reason, they h...

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Detalhes bibliográficos
Main Authors: Galichet, Christophe, Lovell-Badge, Robin, Rizzoti, Karine
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2897851/
https://ncbi.nlm.nih.gov/pubmed/20625432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011443
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