Effects of CRN04894, a Nonpeptide Orally Bioavailable ACTH Antagonist, on Corticosterone in Rodent Models of ACTH Excess

CRN04894 is an orally administered nonpeptide that is a potent and selective antagonist for adrenocorticotropic hormone (ACTH) acting at the melanocortin 2 receptor (MC2R) and is currently under development for the treatment of diseases of ACTH excess such as Cushing’s disease, congenital adrenal hy...

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書目詳細資料
發表在:J Endocr Soc
Main Authors: Fowler, Melissa A, Kusnetzow, Ana Karin, Han, Sangdon, Reinhart, Greg, Kim, Sun Hee, Johns, Michael, Kredel, Taylor A, Antwan, Agnes, Athanacio, Jon, Tsivkovski, Oleg, Luo, Rosa, Madan, Ajay, Zhu, Yun Fei, Betz, Stephen F, Struthers, Scott, Markison, Stacy
格式: Artigo
語言:Inglês
出版: Oxford University Press 2021
主題:
Adrenal
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090401/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.337
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