SAT-169 Selective Nonpeptide Somatostatin Subtype 5 (sst5) Agonists Suppress Glucose- and Sulfonylurea-Induced Insulin Secretion in Rats

Congenital hyperinsulinism (CHI) results from mutations within the insulin secretion pathway and is characterized by excessive and/or inappropriate insulin secretion by pancreatic islet β-cells. CHI is the most common cause of persistent hypoglycemia in newborns and infants and is estimated to affec...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Sturchler, Emmanuel, Fowler, Melissa, Athanacio, Jon, Kredel, Taylor, Johns, Michael, Zhao, Jian, Wang, Shimiao, Luo, Rosa, Kusnetzow, Ana, Zhu, Yun Fei, Madan, Ajay, Struthers, Scott, Betz, Stephen, Markison, Stacy
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2019
Assuntos:
Diabetes Mellitus and Glucose Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6552315/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/js.2019-SAT-169
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