Deletion of Nuclear Receptor Constitutive Androstane Receptor CAR Increases Anxiety and Lowers Androgen Levels

The orphan nuclear receptor, Constitutive Androstane Receptor (CAR, NR1I3) is primarily known to regulate the transcriptional networks involved in detoxification. We have identified a novel extra-hepatic role of CAR in regulating androgen levels and modulating testis function. Previous data has reve...

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Bibliographic Details
Published in:J Endocr Soc
Main Authors: Hernandez, Juan P, Asokakumar, Anjana, Xiao, Rui, Moore, David D, Anakk, Sayeepriyadarshini
Format: Artigo
Language:Inglês
Published: Oxford University Press 2021
Subjects:
Steroid Hormones and Receptors
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090177/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1641
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