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Deletion of Nuclear Receptor Constitutive Androstane Receptor CAR Increases Anxiety and Lowers Androgen Levels

The orphan nuclear receptor, Constitutive Androstane Receptor (CAR, NR1I3) is primarily known to regulate the transcriptional networks involved in detoxification. We have identified a novel extra-hepatic role of CAR in regulating androgen levels and modulating testis function. Previous data has reve...

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Dettagli Bibliografici
Pubblicato in:J Endocr Soc
Autori principali: Hernandez, Juan P, Asokakumar, Anjana, Xiao, Rui, Moore, David D, Anakk, Sayeepriyadarshini
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090177/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1641
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