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Deletion of Nuclear Receptor Constitutive Androstane Receptor CAR Increases Anxiety and Lowers Androgen Levels

The orphan nuclear receptor, Constitutive Androstane Receptor (CAR, NR1I3) is primarily known to regulate the transcriptional networks involved in detoxification. We have identified a novel extra-hepatic role of CAR in regulating androgen levels and modulating testis function. Previous data has reve...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Hernandez, Juan P, Asokakumar, Anjana, Xiao, Rui, Moore, David D, Anakk, Sayeepriyadarshini
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8090177/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.1641
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