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LGR4 and Its Extracellular Domain as Novel Regulators of ß-Cell Survival and Proliferation
Our lab has shown that RANK (Receptor activator of the NF-κB) by interacting with its ligand, RANKL, inhibits ß-cell proliferation and survival; which can be reversed by Osteoprotegerin (OPG). Recently, the G protein-coupled receptor LGR4 (leucine-rich repeat-containing G protein-coupled receptor 4)...
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| Veröffentlicht in: | J Endocr Soc |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2021
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8089736/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.656 |
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