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LGR4 and Its Extracellular Domain as Novel Regulators of ß-Cell Survival and Proliferation

Our lab has shown that RANK (Receptor activator of the NF-κB) by interacting with its ligand, RANKL, inhibits ß-cell proliferation and survival; which can be reversed by Osteoprotegerin (OPG). Recently, the G protein-coupled receptor LGR4 (leucine-rich repeat-containing G protein-coupled receptor 4)...

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Detalhes bibliográficos
Publicado no:J Endocr Soc
Main Authors: Filipowska, Joanna K, Kondegowda, Nagesha G, Vasavada, Rupangi C
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089736/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.656
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