Lactogens Reduce Endoplasmic Reticulum Stress–Induced Rodent and Human β-Cell Death and Diabetes Incidence in Akita Mice

Diabetes occurs due to a loss of functional β-cells, resulting from β-cell death and dysfunction. Lactogens protect rodent and human β-cells in vitro and in vivo against triggers of β-cell cytotoxicity relevant to diabetes, many of which converge onto a common pathway of endoplasmic reticulum (ER) s...

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Detalhes bibliográficos
Publicado no:Diabetes
Main Authors: Li, Rosemary, Kondegowda, Nagesha Guthalu, Filipowska, Joanna, Hampton, Rollie F., Leblanc, Silvia, Garcia-Ocana, Adolfo, Vasavada, Rupangi C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2020
Assuntos:
Islet Studies
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306119/
https://ncbi.nlm.nih.gov/pubmed/32332156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0909
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