A Prospective Cross-Over Study of Tissue Glucocorticoid Metabolism in Patients With Adrenal Insufficiency: The Effects of Dual-Release Hydrocortisone Therapy

Background: Patients with adrenal insufficiency (AI) require life-long glucocorticoid (GC) replacement therapy. Within tissues, cortisol (F) availability is under the control of the isozymes of 11β-hydroxysteroid dehydrogenase (11β-HSD). We hypothesize that GC metabolism is altered in patients with...

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Detaylı Bibliyografya
Yayımlandı:J Endocr Soc
Asıl Yazarlar: Dineen, Rosemary Anne, Martin-Grace, Julie, Saeed Ahmed, Khalid Mohamed, Taylor, Angela Elizabeth, Shaheen, Fozia, Schiffer, Lina, Gilligan, Lorna, Frizelle, Isolda Mary, Gunness, Anjuli, Garrahy, Aoife, Hannon, Anne marie, O’Reilly, Michael William, Smith, Diarmuid, McDermott, John, Marie-Louise, Healy, Agha, Amar, Pazderska, Agnieszka, Gibney, James, Behan, Lucy-Ann, Arlt, Wiebke, Thompson, Chris John, Sherlock, Mark
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2021
Konular:
Adrenal
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089674/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.150
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