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A Prospective Cross-Over Study of Tissue Glucocorticoid Metabolism in Patients With Adrenal Insufficiency: The Effects of Dual-Release Hydrocortisone Therapy

Background: Patients with adrenal insufficiency (AI) require life-long glucocorticoid (GC) replacement therapy. Within tissues, cortisol (F) availability is under the control of the isozymes of 11β-hydroxysteroid dehydrogenase (11β-HSD). We hypothesize that GC metabolism is altered in patients with...

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書目詳細資料
發表在:J Endocr Soc
Main Authors: Dineen, Rosemary Anne, Martin-Grace, Julie, Saeed Ahmed, Khalid Mohamed, Taylor, Angela Elizabeth, Shaheen, Fozia, Schiffer, Lina, Gilligan, Lorna, Frizelle, Isolda Mary, Gunness, Anjuli, Garrahy, Aoife, Hannon, Anne marie, O’Reilly, Michael William, Smith, Diarmuid, McDermott, John, Marie-Louise, Healy, Agha, Amar, Pazderska, Agnieszka, Gibney, James, Behan, Lucy-Ann, Arlt, Wiebke, Thompson, Chris John, Sherlock, Mark
格式: Artigo
語言:Inglês
出版: Oxford University Press 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089674/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jendso/bvab048.150
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