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The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy

BACKGROUND: Glucocorticoid therapy is the most common cause of iatrogenic osteoporosis. Less is known regarding the effect of glucocorticoids when used as replacement therapy on bone remodelling in patients with adrenal insufficiency. Enhanced intracellular conversion of inactive cortisone to active...

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Bibliographic Details
Published in:BMC Endocr Disord
Main Authors: Dineen, Rosemary, Behan, Lucy-Ann, Kelleher, Grainne, Hannon, Mark J., Brady, Jennifer J., Rogers, Bairbre, Keevil, Brian G., Tormey, William, Smith, Diarmuid, Thompson, Christopher J., McKenna, Malachi J., Arlt, Wiebke, Stewart, Paul M., Agha, Amar, Sherlock, Mark
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547490/
https://ncbi.nlm.nih.gov/pubmed/33036588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12902-020-00633-1
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