The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy

BACKGROUND: Glucocorticoid therapy is the most common cause of iatrogenic osteoporosis. Less is known regarding the effect of glucocorticoids when used as replacement therapy on bone remodelling in patients with adrenal insufficiency. Enhanced intracellular conversion of inactive cortisone to active...

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Vydáno v:BMC Endocr Disord
Hlavní autoři: Dineen, Rosemary, Behan, Lucy-Ann, Kelleher, Grainne, Hannon, Mark J., Brady, Jennifer J., Rogers, Bairbre, Keevil, Brian G., Tormey, William, Smith, Diarmuid, Thompson, Christopher J., McKenna, Malachi J., Arlt, Wiebke, Stewart, Paul M., Agha, Amar, Sherlock, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7547490/
https://ncbi.nlm.nih.gov/pubmed/33036588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12902-020-00633-1
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