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PINK1‐mediated mitophagy maintains pluripotency through optineurin

OBJECTIVES: Dysfunction of autophagy results in accumulation of depolarized mitochondria and breakdown of self‐renewal and pluripotency in ESCs. However, the regulators that control how mitochondria are degraded by autophagy for pluripotency regulation remains largely unknown. This study aims to dis...

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Detalhes bibliográficos
Publicado no:Cell Prolif
Main Authors: Wang, Chaoqun, Liu, Kun, Cao, Jiani, Wang, Liang, Zhao, Qian, Li, Zheng, Zhang, Honghai, Chen, Quan, Zhao, Tongbiao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088463/
https://ncbi.nlm.nih.gov/pubmed/33931895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.13034
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