The PINK1/PARK2/optineurin pathway of mitophagy is activated for protection in septic acute kidney injury

Sepsis is the major cause of acute kidney injury (AKI) associated with high mortality rates. Mitochondrial dysfunction contributes to the pathophysiology of septic AKI. Mitophagy is an important mitochondrial quality control mechanism that selectively eliminates damaged mitochondria, but its role an...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Wang, Ying, Zhu, Jiefu, Liu, Zhiwen, Shu, Shaoqun, Fu, Ying, Liu, Yuxue, Cai, Juan, Tang, Chengyuan, Liu, Yu, Yin, Xiaoming, Dong, Zheng
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7606859/
https://ncbi.nlm.nih.gov/pubmed/33137712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101767
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