Endoplasmic reticulum stress is activated in post-ischemic kidneys to promote chronic kidney disease

BACKGROUND: Acute kidney injury (AKI) may lead to the development of chronic kidney disease (CKD), i.e. AKI-CKD transition, but the underlying mechanism remains largely unclear. Endoplasmic reticulum (ER) stress is characterized by the accumulation of unfolded or misfolded proteins in ER resulting i...

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Detalles Bibliográficos
Publicado en:EBioMedicine
Main Authors: Shu, Shaoqun, Zhu, Jiefu, Liu, Zhiwen, Tang, Chengyuan, Cai, Juan, Dong, Zheng
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
Assuntos:
Research paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6286638/
https://ncbi.nlm.nih.gov/pubmed/30314894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.10.006
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