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PINK1‐mediated mitophagy maintains pluripotency through optineurin

OBJECTIVES: Dysfunction of autophagy results in accumulation of depolarized mitochondria and breakdown of self‐renewal and pluripotency in ESCs. However, the regulators that control how mitochondria are degraded by autophagy for pluripotency regulation remains largely unknown. This study aims to dis...

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Vydáno v:Cell Prolif
Hlavní autoři: Wang, Chaoqun, Liu, Kun, Cao, Jiani, Wang, Liang, Zhao, Qian, Li, Zheng, Zhang, Honghai, Chen, Quan, Zhao, Tongbiao
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088463/
https://ncbi.nlm.nih.gov/pubmed/33931895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.13034
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