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PINK1‐mediated mitophagy maintains pluripotency through optineurin

OBJECTIVES: Dysfunction of autophagy results in accumulation of depolarized mitochondria and breakdown of self‐renewal and pluripotency in ESCs. However, the regulators that control how mitochondria are degraded by autophagy for pluripotency regulation remains largely unknown. This study aims to dis...

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Bibliografski detalji
Izdano u:Cell Prolif
Glavni autori: Wang, Chaoqun, Liu, Kun, Cao, Jiani, Wang, Liang, Zhao, Qian, Li, Zheng, Zhang, Honghai, Chen, Quan, Zhao, Tongbiao
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088463/
https://ncbi.nlm.nih.gov/pubmed/33931895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cpr.13034
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