Suppression of optineurin impairs the progression of hepatocellular carcinoma through regulating mitophagy

Autophagy removes damaged organelles to inhibit malignant transformation during tumor initiation. Once a cancer matures, it uses the autophagic pathway as an energy source. Optineurin (OPTN) is an autophagy adaptor protein that recruits microtubule‐associated protein 1 light chain 3, an autophagosom...

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Bibliografische gegevens
Gepubliceerd in:Cancer Med
Hoofdauteurs: Inokuchi, Shoichi, Yoshizumi, Tomoharu, Toshima, Takeo, Itoh, Shinji, Yugawa, Kyohei, Harada, Noboru, Mori, Hiroyuki, Fukuhara, Takasuke, Matsuura, Yoshiharu, Mori, Masaki
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2021
Onderwerpen:
Clinical Cancer Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940236/
https://ncbi.nlm.nih.gov/pubmed/33600074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.3519
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