Modulation of Nqo1 activity intercepts anoikis resistance and reduces metastatic potential of hepatocellular carcinoma

The processing of intracellular reactive oxygen species (ROS) by nuclear factor erythroid‐derived 2‐like 2 (Nrf2) and NADPH quinone oxidoreductase 1 (Nqo1) is important for tumor metastasis. However, the clinical and biological significance of Nrf2/Nqo1 expression in hepatocellular carcinoma (HCC) r...

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Bibliographic Details
Published in:Cancer Sci
Main Authors: Shimokawa, Masahiro, Yoshizumi, Tomoharu, Itoh, Shinji, Iseda, Norifumi, Sakata, Kazuhito, Yugawa, Kyohei, Toshima, Takeo, Harada, Noboru, Ikegami, Toru, Mori, Masaki
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2020
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7156873/
https://ncbi.nlm.nih.gov/pubmed/31968140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.14320
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