Inducible knockout of ΔNp63 alters cell polarity and metabolism during pubertal mammary gland development

The ΔNp63 isoform of the p53-family transcription factor Trp63 is a key regulator of mammary epithelial stem cells that is involved in breast cancer development. To investigate the role of ΔNp63 at different stages of normal mammary gland development, we generated a ΔNp63-inducible conditional knock...

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Gepubliceerd in:FEBS Lett
Hoofdauteurs: Kumar, Sushil, Nandi, Ajeya, Mahesh, Aakash, Sinha, Satrajit, Flores, Elsa, Chakrabarti, Rumela
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8088331/
https://ncbi.nlm.nih.gov/pubmed/31794060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1873-3468.13703
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