ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation

The transcription factor p63 is important in the development of the skin as p63-null mice exhibit striking defects in embryonic epidermal morphogenesis. Understanding the mechanisms that underlie this phenotype is complicated by the existence of multiple p63 isoforms, including TAp63 and ΔNp63. To i...

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Detalhes bibliográficos
Main Authors: Romano, Rose-Anne, Smalley, Kirsten, Magraw, Caitlin, Serna, Vanida Ann, Kurita, Takeshi, Raghavan, Srikala, Sinha, Satrajit
Formato: Artigo
Idioma:Inglês
Publicado em: Company of Biologists 2012
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3265062/
https://ncbi.nlm.nih.gov/pubmed/22274697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.071191
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