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ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation
The transcription factor p63 is important in the development of the skin as p63-null mice exhibit striking defects in embryonic epidermal morphogenesis. Understanding the mechanisms that underlie this phenotype is complicated by the existence of multiple p63 isoforms, including TAp63 and ΔNp63. To i...
Uloženo v:
Hlavní autoři: | , , , , , , |
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Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Company of Biologists
2012
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265062/ https://ncbi.nlm.nih.gov/pubmed/22274697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.071191 |
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