ΔNp63 promotes stem cell activity in mammary gland development and basal-like breast cancer by enhancing Fzd7 expression and Wnt signaling

Emerging evidence suggests that cancer is populated and maintained by tumor initiating cells (TICs) with stem-like properties similar to that of adult tissue stem cells. Despite recent advances, the molecular regulatory mechanisms that may be shared between normal and malignant stem cells remain poo...

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Hauptverfasser: Chakrabarti, Rumela, Wei, Yong, Hwang, Julie, Hang, Xiang, Blanco, Mario Andres, Choudhury, Abrar, Tiede, Benjamin, Romano, Rose-Anne, DeCoste, Christina, Mercatali, Laura, Ibrahim, Toni, Amadori, Dino, Kannan, Nagarajan, Eaves, Connie J, Sinha, Satrajit, Kang, Yibin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183725/
https://ncbi.nlm.nih.gov/pubmed/25241036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3040
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