ΔNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is particularly aggressive, with enhanced incidence of tumor relapse, resistance to chemotherapy, and metastases. As the mechanistic basis for this aggressive phenotype is unclear, treatment options are limited. Here, we showed an increased population of myeloid-...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Kumar, Sushil, Wilkes, David W., Samuel, Nina, Blanco, Mario Andres, Nayak, Anupma, Alicea-Torres, Kevin, Gluck, Christian, Sinha, Satrajit, Gabrilovich, Dmitry, Chakrabarti, Rumela
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2018
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205409/
https://ncbi.nlm.nih.gov/pubmed/30295647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99673
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