ΔNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is particularly aggressive, with enhanced incidence of tumor relapse, resistance to chemotherapy, and metastases. As the mechanistic basis for this aggressive phenotype is unclear, treatment options are limited. Here, we showed an increased population of myeloid-...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Kumar, Sushil, Wilkes, David W., Samuel, Nina, Blanco, Mario Andres, Nayak, Anupma, Alicea-Torres, Kevin, Gluck, Christian, Sinha, Satrajit, Gabrilovich, Dmitry, Chakrabarti, Rumela
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2018
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205409/
https://ncbi.nlm.nih.gov/pubmed/30295647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99673
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