ΔNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is particularly aggressive, with enhanced incidence of tumor relapse, resistance to chemotherapy, and metastases. As the mechanistic basis for this aggressive phenotype is unclear, treatment options are limited. Here, we showed an increased population of myeloid-...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Clin Invest
Autori principali: Kumar, Sushil, Wilkes, David W., Samuel, Nina, Blanco, Mario Andres, Nayak, Anupma, Alicea-Torres, Kevin, Gluck, Christian, Sinha, Satrajit, Gabrilovich, Dmitry, Chakrabarti, Rumela
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205409/
https://ncbi.nlm.nih.gov/pubmed/30295647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99673
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi