ΔNp63-driven recruitment of myeloid-derived suppressor cells promotes metastasis in triple-negative breast cancer

Triple-negative breast cancer (TNBC) is particularly aggressive, with enhanced incidence of tumor relapse, resistance to chemotherapy, and metastases. As the mechanistic basis for this aggressive phenotype is unclear, treatment options are limited. Here, we showed an increased population of myeloid-...

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Библиографические подробности
Опубликовано в: :J Clin Invest
Главные авторы: Kumar, Sushil, Wilkes, David W., Samuel, Nina, Blanco, Mario Andres, Nayak, Anupma, Alicea-Torres, Kevin, Gluck, Christian, Sinha, Satrajit, Gabrilovich, Dmitry, Chakrabarti, Rumela
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6205409/
https://ncbi.nlm.nih.gov/pubmed/30295647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99673
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