CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status

INTRODUCTION: Cerebrospinal fluid (CSF) total tau (t‐tau) and phosphorylated tau (p‐tau) are biomarkers of Alzheimer's disease (AD), yet much is unknown about AD‐associated changes in tau metabolism and tau tangle etiology. METHODS: We assessed the variation of t‐tau and p‐tau explained by 38 p...

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Dettagli Bibliografici
Pubblicato in:Alzheimers Dement (Amst)
Autori principali: Dong, Ruocheng, Darst, Burcu F., Deming, Yuetiva, Ma, Yue, Lu, Qiongshi, Zetterberg, Henrik, Blennow, Kaj, Carlsson, Cynthia M., Johnson, Sterling C., Asthana, Sanjay, Engelman, Corinne D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
Soggetti:
Cerebrospinal Fluid Biomarkers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087982/
https://ncbi.nlm.nih.gov/pubmed/33969169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12167
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