CSF sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer's disease

Cellular studies suggest sphingolipids may cause or accelerate amyloid-beta (Aβ) and tau pathology but in vivo human studies are lacking. We determined cerebrospinal fluid (CSF) levels of sphingolipids (ceramides, sphingomyelins), amyloid-beta (Aβ1–42, AβX-38, AβX-40, AβX-42) and tau (T-tau, p-tau18...

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Main Authors: Mielke, Michelle M., Haughey, Norman J., Bandaru, V.V.R., Zetterberg, Henrik, Blennow, Kaj, Andreasson, Ulf, Johnson, Sterling C., Gleason, Carey E., Blazel, Hanna M., Puglielli, Luigi, Sager, Mark A., Asthana, Sanjay, Carlsson, Cynthia M.
Format: Artigo
Jezik:Inglês
Izdano: 2014
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170854/
https://ncbi.nlm.nih.gov/pubmed/24952994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.05.019
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