CSF sphingolipids, β-amyloid, and tau in adults at risk for Alzheimer's disease

Cellular studies suggest sphingolipids may cause or accelerate amyloid-beta (Aβ) and tau pathology but in vivo human studies are lacking. We determined cerebrospinal fluid (CSF) levels of sphingolipids (ceramides, sphingomyelins), amyloid-beta (Aβ1–42, AβX-38, AβX-40, AβX-42) and tau (T-tau, p-tau18...

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Hauptverfasser: Mielke, Michelle M., Haughey, Norman J., Bandaru, V.V.R., Zetterberg, Henrik, Blennow, Kaj, Andreasson, Ulf, Johnson, Sterling C., Gleason, Carey E., Blazel, Hanna M., Puglielli, Luigi, Sager, Mark A., Asthana, Sanjay, Carlsson, Cynthia M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4170854/
https://ncbi.nlm.nih.gov/pubmed/24952994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neurobiolaging.2014.05.019
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