CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status

INTRODUCTION: Cerebrospinal fluid (CSF) total tau (t‐tau) and phosphorylated tau (p‐tau) are biomarkers of Alzheimer's disease (AD), yet much is unknown about AD‐associated changes in tau metabolism and tau tangle etiology. METHODS: We assessed the variation of t‐tau and p‐tau explained by 38 p...

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Bibliografiske detaljer
Udgivet i:Alzheimers Dement (Amst)
Main Authors: Dong, Ruocheng, Darst, Burcu F., Deming, Yuetiva, Ma, Yue, Lu, Qiongshi, Zetterberg, Henrik, Blennow, Kaj, Carlsson, Cynthia M., Johnson, Sterling C., Asthana, Sanjay, Engelman, Corinne D.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Cerebrospinal Fluid Biomarkers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087982/
https://ncbi.nlm.nih.gov/pubmed/33969169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12167
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