CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status

INTRODUCTION: Cerebrospinal fluid (CSF) total tau (t‐tau) and phosphorylated tau (p‐tau) are biomarkers of Alzheimer's disease (AD), yet much is unknown about AD‐associated changes in tau metabolism and tau tangle etiology. METHODS: We assessed the variation of t‐tau and p‐tau explained by 38 p...

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Vydáno v:Alzheimers Dement (Amst)
Hlavní autoři: Dong, Ruocheng, Darst, Burcu F., Deming, Yuetiva, Ma, Yue, Lu, Qiongshi, Zetterberg, Henrik, Blennow, Kaj, Carlsson, Cynthia M., Johnson, Sterling C., Asthana, Sanjay, Engelman, Corinne D.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2021
Témata:
Cerebrospinal Fluid Biomarkers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087982/
https://ncbi.nlm.nih.gov/pubmed/33969169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12167
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