CSF metabolites associate with CSF tau and improve prediction of Alzheimer's disease status

INTRODUCTION: Cerebrospinal fluid (CSF) total tau (t‐tau) and phosphorylated tau (p‐tau) are biomarkers of Alzheimer's disease (AD), yet much is unknown about AD‐associated changes in tau metabolism and tau tangle etiology. METHODS: We assessed the variation of t‐tau and p‐tau explained by 38 p...

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Detalhes bibliográficos
Publicado no:Alzheimers Dement (Amst)
Main Authors: Dong, Ruocheng, Darst, Burcu F., Deming, Yuetiva, Ma, Yue, Lu, Qiongshi, Zetterberg, Henrik, Blennow, Kaj, Carlsson, Cynthia M., Johnson, Sterling C., Asthana, Sanjay, Engelman, Corinne D.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Cerebrospinal Fluid Biomarkers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8087982/
https://ncbi.nlm.nih.gov/pubmed/33969169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dad2.12167
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