The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease

BACKGROUND: Trimethylamine N-oxide (TMAO), a small molecule produced by the metaorganismal metabolism of dietary choline, has been implicated in human disease pathogenesis, including known risk factors for Alzheimer’s disease (AD), such as metabolic, cardiovascular, and cerebrovascular disease. METH...

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Détails bibliographiques
Publié dans:Alzheimers Res Ther
Auteurs principaux: Vogt, Nicholas M., Romano, Kymberleigh A., Darst, Burcu F., Engelman, Corinne D., Johnson, Sterling C., Carlsson, Cynthia M., Asthana, Sanjay, Blennow, Kaj, Zetterberg, Henrik, Bendlin, Barbara B., Rey, Federico E.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6303862/
https://ncbi.nlm.nih.gov/pubmed/30579367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0451-2
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