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Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine-N-Oxide

Choline is a water-soluble nutrient essential for human life. Gut microbial metabolism of choline results in the production of trimethylamine (TMA), which upon absorption by the host is converted in the liver to trimethylamine-N-oxide (TMAO). Recent studies revealed that TMAO exacerbates atheroscler...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Romano, Kymberleigh A., Vivas, Eugenio I., Amador-Noguez, Daniel, Rey, Federico E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4453578/
https://ncbi.nlm.nih.gov/pubmed/25784704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02481-14
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