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Prognostic value of choline and betaine depends on intestinal microbiota-generated metabolite trimethylamine-N-oxide

AIMS: Recent metabolomics and animal model studies show trimethylamine-N-oxide (TMAO), an intestinal microbiota-dependent metabolite formed from dietary trimethylamine-containing nutrients such as phosphatidylcholine (PC), choline, and carnitine, is linked to coronary artery disease pathogenesis. Ou...

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Bibliografiske detaljer
Main Authors: Wang, Zeneng, Tang, W. H. Wilson, Buffa, Jennifer A., Fu, Xiaoming, Britt, Earl B., Koeth, Robert A., Levison, Bruce S., Fan, Yiying, Wu, Yuping, Hazen, Stanley L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977137/
https://ncbi.nlm.nih.gov/pubmed/24497336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehu002
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