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LAMC2 promotes cancer progression and gemcitabine resistance through modulation of EMT and ATP-binding cassette transporters in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is an aggressive disease with poor prognosis. Gemcitabine remains an effective option for the majority of PDAC patients. Unfortunately, currently no reliable prognostic and predictive biomarkers of therapeutic response are available for the patients with PDAC....

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Detalhes bibliográficos
Publicado no:Carcinogenesis
Main Authors: Okada, Yasuyuki, Takahashi, Naoki, Takayama, Tetsuji, Goel, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8086766/
https://ncbi.nlm.nih.gov/pubmed/33624791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgab011
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