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Identification of LAMC2 as a prognostic and predictive biomarker for determining response to gemcitabine-based therapy in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies. While the extracellular matrix (ECM) components plays an integral role in PDAC pathogenesis and mediating chemoresistance, its role in predicting response to chemotherapy in PDAC patients remains unclear. MET...

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Detalhes bibliográficos
Publicado no:Eur J Cancer
Main Authors: Okada, Yasuyuki, Nishiwada, Satoshi, Yamamura, Kensuke, Sho, Masayuki, Baba, Hideo, Takayama, Tetsuji, Goel, Ajay
Formato: Artigo
Idioma:Inglês
Publicado em: 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940597/
https://ncbi.nlm.nih.gov/pubmed/33607476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2020.12.031
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