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Identification of LAMC2 as a prognostic and predictive biomarker for determining response to gemcitabine-based therapy in pancreatic ductal adenocarcinoma

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies. While the extracellular matrix (ECM) components plays an integral role in PDAC pathogenesis and mediating chemoresistance, its role in predicting response to chemotherapy in PDAC patients remains unclear. MET...

詳細記述

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書誌詳細
出版年:Eur J Cancer
主要な著者: Okada, Yasuyuki, Nishiwada, Satoshi, Yamamura, Kensuke, Sho, Masayuki, Baba, Hideo, Takayama, Tetsuji, Goel, Ajay
フォーマット: Artigo
言語:Inglês
出版事項: 2021
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7940597/
https://ncbi.nlm.nih.gov/pubmed/33607476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejca.2020.12.031
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