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Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma
Pancreatic ductal adenocarcinoma (PDAC) is an aggressive cancer with marked chemoresistance and a 5-year survival rate of 7%. The integrated stress response (ISR) is a cytoprotective pathway initiated in response to exposure to various environmental stimuli. We used pancreatic cancer cells (PCCs) th...
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| Udgivet i: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4632294/ https://ncbi.nlm.nih.gov/pubmed/26469962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.264 |
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