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MARS: leveraging allelic heterogeneity to increase power of association testing
In standard genome-wide association studies (GWAS), the standard association test is underpowered to detect associations between loci with multiple causal variants with small effect sizes. We propose a statistical method, Model-based Association test Reflecting causal Status (MARS), that finds assoc...
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| Publicado en: | Genome Biol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2021
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8086090/ https://ncbi.nlm.nih.gov/pubmed/33931127 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-021-02353-8 |
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