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Multiple testing correction in linear mixed models

BACKGROUND: Multiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes into account the correlation structure of the...

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Vydáno v:Genome Biol
Hlavní autoři: Joo, Jong Wha J., Hormozdiari, Farhad, Han, Buhm, Eskin, Eleazar
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818520/
https://ncbi.nlm.nih.gov/pubmed/27039378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0903-6
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