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Multiple testing correction in linear mixed models

BACKGROUND: Multiple hypothesis testing is a major issue in genome-wide association studies (GWAS), which often analyze millions of markers. The permutation test is considered to be the gold standard in multiple testing correction as it accurately takes into account the correlation structure of the...

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Pubblicato in:Genome Biol
Autori principali: Joo, Jong Wha J., Hormozdiari, Farhad, Han, Buhm, Eskin, Eleazar
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4818520/
https://ncbi.nlm.nih.gov/pubmed/27039378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-0903-6
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