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Improving Imputation Accuracy by Inferring Causal Variants in Genetic Studies

Genotype imputation has been widely utilized for two reasons in the analysis of genome-wide association studies (GWAS). One reason is to increase the power for association studies when causal single nucleotide polymorphisms are not collected in the GWAS. The second reason is to aid the interpretatio...

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Detalhes bibliográficos
Publicado no:J Comput Biol
Main Authors: Wu, Yue, Hormozdiari, Farhad, Joo, Jong Wha J., Eskin, Eleazar
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6856942/
https://ncbi.nlm.nih.gov/pubmed/30272994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cmb.2018.0139
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