Widespread Allelic Heterogeneity in Complex Traits

Recent successes in genome-wide association studies (GWASs) make it possible to address important questions about the genetic architecture of complex traits, such as allele frequency and effect size. One lesser-known aspect of complex traits is the extent of allelic heterogeneity (AH) arising from m...

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Vydáno v:Am J Hum Genet
Hlavní autoři: Hormozdiari, Farhad, Zhu, Anthony, Kichaev, Gleb, Ju, Chelsea J.-T., Segrè, Ayellet V., Joo, Jong Wha J., Won, Hyejung, Sankararaman, Sriram, Pasaniuc, Bogdan, Shifman, Sagiv, Eskin, Eleazar
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2017
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5420356/
https://ncbi.nlm.nih.gov/pubmed/28475861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2017.04.005
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