USP44 Stabilizes DDB2 to Facilitate Nucleotide Excision Repair and Prevent Tumors

Nucleotide excision repair (NER) is a pathway involved in the repair of a variety of potentially mutagenic lesions that distort the DNA double helix. The ubiquitin E3-ligase complex UV-DDB is required for the recognition and repair of UV-induced cyclobutane pyrimidine dimers (CPDs) lesions through N...

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Detalhes bibliográficos
Publicado no:Front Cell Dev Biol
Main Authors: Zhang, Ying, Mandemaker, Imke K., Matsumoto, Syota, Foreman, Oded, Holland, Christopher P., Lloyd, Whitney R., Sugasawa, Kaoru, Vermeulen, Wim, Marteijn, Jurgen A., Galardy, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8085418/
https://ncbi.nlm.nih.gov/pubmed/33937266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2021.663411
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