Genomic features of exceptional response in vemurafenib ± cobimetinib–treated patients with BRAF(V600)-mutated metastatic melanoma

PURPOSE: Previous investigations identified transcriptional signatures associated with innate resistance to anti–programmed cell death protein 1 therapy in melanoma. This analysis aimed to increase understanding of the role of baseline genetic features in the variability of response to BRAF and MEK...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:Clin Cancer Res
Hlavní autoři: Yan, Yibing, Wongchenko, Matthew J., Robert, Caroline, Larkin, James, Ascierto, Paolo A., Dréno, Brigitte, Maio, Michele, Garbe, Claus, Chapman, Paul B., Sosman, Jeffrey A., Shi, Zhen, Koeppen, Hartmut, Hsu, Jessie J., Chang, Ilsung, Caro, Ivor, Rooney, Isabelle, McArthur, Grant A., Ribas, Antoni
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8083896/
https://ncbi.nlm.nih.gov/pubmed/30824584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0720
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky