DDX3X coordinates host defense against influenza virus by activating the NLRP3 inflammasome and type I interferon response

Viruses and hosts have coevolved for millions of years, leading to the development of complex host–pathogen interactions. Influenza A virus (IAV) causes severe pulmonary pathology and is a recurrent threat to human health. Innate immune sensing of IAV triggers a complex chain of host responses. IAV...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kesavardhana, Sannula, Samir, Parimal, Zheng, Min, Malireddi, R.K. Subbarao, Karki, Rajendra, Sharma, Bhesh Raj, Place, David E., Briard, Benoit, Vogel, Peter, Kanneganti, Thirumala-Devi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8081917/
https://ncbi.nlm.nih.gov/pubmed/33766561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100579
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